A Man Inhaled Paint Thinner Fumes For 7 Hours. This Is What Happened To His Organs.

2023-03-31

[public] 366K views, 54.2K likes, dislikes audio only

All references below. Inhalant misuse is well-documented to cause permanent damage to the body. The neurological damage can be acute, and continued misuse will progress to multi-organ damage. Sudden cardiac death is also known to happen with this misuse, along with a variety of additional problems.

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Toluene Toxic Leukoencephalopathy Image case courtesy of Dr Chee Kok Yoon, Radiopaedia.org, rID: 17082

These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

References:

Syndromes of toluene sniffing in adults. Ann Intern Med. 1981;94:758-762.

Glue-sniffing and distal renal tubular acidosis: sticking to the facts. https://pubmed.ncbi.nlm.nih.gov/1912400/

Laboratory approach for diagnosis of toluene-based inhalant abuse in a clinical setting.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766772/

Neurotoxicity of solvents in brain of glue abusers. https://pubmed.ncbi.nlm.nih.gov/21783541/

Neural basis of inhalant abuse. https://pubmed.ncbi.nlm.nih.gov/9716942/

A rare but serious case of toluene-induced sudden sniffing death. https://www.sciencedirect.com/science/article/pii/S2211558715000953

Hydrocarbon toxicity: A review. https://www.tandfonline.com/doi/full/10.3109/15563650.2014.923904

Inhalant Misuse in children and adolescents. UpToDate. Accessed 28 Mar 2023.

Effect of benzene, toluene, xylene on the .. quality of exposed workers. https://pubmed.ncbi.nlm.nih.gov/11601277/

Effects of pH on Potassium: New Explanations for Old Observations. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231780

THE EFFECT IN HUMANS OF EXTRACELLULAR pH CHANGE ON THE RELATIONSHIP BETWEEN SERUM POTASSIUM CONCENTRATION AND INTRACELLULAR POTASSIUM. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441665/

MR Imaging of "Spray Heads": Toluene Abuse via Aerosol Paint Inhalation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332768/pdf/8237703.pdf

Review of toluene action: clinical evidence, animal studies and molecular targets. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211428/

On the mechanism of rhabdomyolysis in potassium depletion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC292322

The Effects of Toluene on the Central Nervous System https://academic.oup.com/jnen/article/63/1/1/2916394

Goldfrank’s Toxicologic Emergencies. 11th ed.

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Chubbyemu I make medical videos, telling stories in medicine. These are variations on cases I, or my colleagues, have seen in the past. The main goal of these videos are to tell a story about people, as we each have a unique story to tell. This channel was created in September 2015 as a way for me to create something I could call my own. The earlier videos served to teach me how to make a video, as I have no background in filming, editing, etc. That early content was following trends of the time, learning how best to approach my lack of understanding of video. I hold no responsibility over what you do with your or anyone's body after watching any of my videos. You should not recreate any of the presented situations. These videos are not and are not intended to be medical advice. I do not give individualized medical advice over the internet. I am a licensed provider trained and based in the United States.
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