2020-07-07

[public] 13.0K views, 521 likes, 9.00 dislikes audio only

The Thought Emporium

This project was started last week and is a bit wild. A specific protein from malaria called var2csa was shown in various papers to preferentially stick to more than a dozen types of cancer while ignoring every other cell type. By combining the active part of the protein with the back half of an antibody, it turns the whole assembly into a potent synthetic anti-cancer antibody, which if given to a patient should trigger an antibody dependent cellular cytotoxic effect and eliminate the cancer cells without the need for traditional chemo/radiation.

In this part we'll be going over some changes to the construct that'll make it more effective, talk more about how this works, and explore how pieces of DNA are ordered from synthesis companies.

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