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A Scientist Inhaled 3 Liters Arsine Gas. This Is What Happened To His Kidneys.

2022-08-01

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All references including the book are in this description, see below

Patient MB portrayed by Abram Cutshall, Toast Scientist by Jake Rattan

Special thanks Westminster Christian Academy

Production Assistant Jake Rattan

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These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

References:

Poisoning by arseniuretted hydrogen of hydrogen arsenide, its properties, sources, relations to scientific and industrial operations, symptoms, post-mortem appearances, treatment, and prevention. John Glaister. 1908. https://archive.org/details/poisoningbyarsen00glaiuoft

Tox and Hound Fellow Friday- Metal Hydries I. https://toxandhound.com/toxhound/ff-metal-hydrides/

Sun HD, Ma L, Hu XC, Zhang TD. Treatment of acute promyelocytic leukemia by Ailing-1 therapy with use of syndrome differentiation of traditional Chinese medicine. Chin J Comb Trad Chin Med West Med 1992;12:170-171

Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide. https://www.nejm.org/doi/full/10.1056/NEJM199811053391901

Acute on Chronic Arsenic Poisoning https://www.nejm.org/doi/full/10.1056/NEJMcps1716775

Mechanisms of arsenic: https://sites.dartmouth.edu/toxmetal/arsenic/the-facts-on-arsenic/

Severe acute arsine poisoning treated by plasma exchange. https://www.tandfonline.com/doi/full/10.1080/15563650701502675

Interaction of Arsine with Hemoglobin in Arsine-Induced Hemolysis. https://academic.oup.com/toxsci/article/90/1/142/1692217

Arsine toxicity: Chemical and mechanistic implications https://www.tandfonline.com/doi/abs/10.1080/15287399509532045

Arsenate replacing phosphate - alternative life chemistries and ion. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070116/

Arsenic Binding to Proteins. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797521/

A biography of arsenic and medicine in Hong Kong and China. https://www.hkmj.org/system/files/hkm1112p507.pdf

https://radiopaedia.org/cases/acute-tubular-necrosis-2?lang=us

Memorial Sloan Kettering Image by Kenneth C. Zirkel