2023-10-25

[public] 646K views, 45.3K likes, dislikes audio only

Chubbyemu

Use code EMU50 to get 50% off your first Factor box at https://bit.ly/3qyFRHm!

Patient DC by Kazia Steele, PA Tristyn Smith and Mike Burling

In-depth channel: @HemeReview

Secret Channel: @BigEmus

Music by @Lifeformed ► https://lifeformed.bandcamp.com

Medicine ► https://www.youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FI

Some images by Getty Images

Timestamps:

0:00 Good 🌯 Burrito

0:31 Gotta 😳 go 😳 fast

1:30 Where did it 🦷 go?

2:24 Bacteria 🦠 good?

3:42 Bacteria 🦠 good.

4:47 The right bacteria 🦠 rly good

5:46 What if the wrong species 😳 is growing?

6:33 A wild headache 😩 appears

7:16 Something was 🚽 different

7:51 Bacteria 🦠 coulda been good, but now what?

9:42 Not the species 😨 you want...

11:58 Banana 🍌 good

13:43 A medicolegal 🩺 rationale

16:26 The Swiss Cheese 🧀 Model (of errors like this one)

16:56 I thought I was ok 😃 but now ???

These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

References:

Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal Effects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885049/

C. diff survivor and advocate shares her story. https://blogs.cdc.gov/safehealthcare/c-diff-survivor-and-advocate-shares-her-story-2/

Aetiology of antimicrobial-agent-associated colitis https://pubmed.ncbi.nlm.nih.gov/85818/

Colitis associated with clindamycin therapy https://pubmed.ncbi.nlm.nih.gov/1202637/

Clostridioides difficile infection in adults: Treatment and prevention. UpToDate. Accessed 25 Oct 2023.

Clostridioides difficile infection in adults: Clinical manifestations and diagnosis. UpToDate. Accessed 25 Oct 2023.

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients. https://www.science.org/doi/10.1126/science.aan4236

Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1 https://www.nature.com/articles/s41591-022-01698-2.

Gut microbiome is associated with the clinical response to anti-PD-1 based immunotherapy in hepatobiliary cancers. https://jitc.bmj.com/content/9/12/e003334

Gut Microbiota in Anxiety and Depression: Unveiling the Relationships and Management Options. https://www.mdpi.com/1424-8247/16/4/565

Clostridium difficile colitis following treatment with metronidazole and vancomycin. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428710

Durham Humphrey Amendment of 1951: https://www.gpo.gov/fdsys/pkg/STATUTE-65/pdf/STATUTE-65-Pg648.pdf

IDSA Guidelines C Diff https://journals.lww.com/ajg/fulltext/2021/06000/acg_clinical_guidelines__prevention,_diagnosis,.12.aspx