2022-12-13
[public] 562K views, 71.0K likes, dislikes audio only
4KBased on case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774558/
Music by R. Prince, rearranged; References below
In-depth channel: @HemeReview
Secret channel: @BigEmus
A Scientist Huffed Gas In A Balloon. ► /youtube/video/LnkwxKHVLeU
A Boy Ate 180 Gummy Melatonins For Lunch. ► /youtube/video/nJR8Nfi8wg8
A Man Dry Scooped 35000 Milligrams Caffeine. ► /youtube/video/sylqJ0NEVJw
Medicine (playlist) ► https://www.youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FI
References:
Fatal 3-Nitropropionic Acid Poisoning after Consuming Coconut Water. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774558/
Structural Basis for Malfunction in Complex II. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471735/
A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics. https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4259
3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. https://pubmed.ncbi.nlm.nih.gov/1782616/
3-Nitropropionic Acid - Exogenous Animal Neurotoxin and Possible Human Striatal Toxin. https://web.archive.org/web/20180728043418id_/https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0F665A46A822D5149FDA63A410C448AE/S0317167100032212a.pdf/div-class-title-3-nitropropionic-acid-exogenous-animal-neurotoxin-and-possible-human-striatal-toxin-div.pdf
3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482830/
3-Nitropropionic acid animal model and Huntington' s disease. https://www.sciencedirect.com/science/article/abs/pii/S0149763496000279
A phylogenetic re-evaluation of Arthrinium. doi:10.5598/imafungus.2013.04.01.13
“Dazed and diffused”: making sense of diffusion abnormalities in neurologic pathologies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856542/
Change in the Brain’s White Matter. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201847/
Bongkrekic Acid—a Review of a Lesser-Known Mitochondrial Toxin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440313/
Burkholderia gladioli causes bacterial internal browning in sweetpotato of China. https://link.springer.com/article/10.1007/s13313-020-00691-y
These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.