2018-12-03

[public] 4.65M views, 137K likes, 3.07K dislikes audio only

Chubbyemu

The patient in this case presented to an emergency room in Illinois, 2012.

The opposite case is here: /youtube/video/J3HivpHP-5I

Music by Lifeformed ► https://lifeformed.bandcamp.com

Medicine ► https://www.youtube.com/playlist?list=PL26HeTCO57qcMQB6CrU6QRzEi9tt9l1FI

Spanish translation and dub by Cenzontle Voices, Inc. CDMX

Medical Reviewer: Dr Araceli Morga Vera

A Woman Couldn't Sleep For 9 Days. This Is What Happened To Her Colon. ► /youtube/video/v4vsZw0D9Mo

A Boy Ate 150 Gummy Vitamins For Breakfast. This Is What Happened To His Bones. ► /youtube/video/mZ6nREONy_4

A Mom Drank 3 Gallons Water In 2 Hours. This is What Happened to Her Brain. ► /youtube/video/J3HivpHP-5I

A Girl Suddenly Grew A Beard. Here's What Was Happening In Her Ovaries. ► /youtube/video/4CoSQUexM9Y

A Grandma Ate 1 Pound Chocolate In 6 Hours. This Is What Happened To Her Brain. ► https://www.youtube.com/edit?o=U&video_id=EIzAshQdWeo

These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

Credits:

Patient CG portrayed by Vanessa Banks-Gonzales

Production Assistant: Bradley Williams

Osmotic Demyelination MRI by Dr Brendon Friesen https://radiopaedia.org/cases/trident-sign-osmotic-demyelination

Celiac Disease Pathology by Dr Michael Bonert

References:

[0] Adams RD et. al. Central Pontine Myelinolysis. AMA Arch Neurol Psychiatry. 1959 Feb;81(2):154-72. https://www.ncbi.nlm.nih.gov/pubmed/13616772

[1] Ismail FY. et. al. Clinical semiology and neuroradiologic correlates of acute hypernatremic osmotic challenge in adults: a literature review. AJNR Am J Neuroradiol. 2013 Dec;34(12):2225-32. https://www.ncbi.nlm.nih.gov/pubmed/23413245

[2] Sterns RH. et. al. Osmotic demyelination syndrome following correction of hyponatremia. N Engl J Med. 1986 Jun 12;314(24):1535-42. https://www.ncbi.nlm.nih.gov/pubmed/3713747

[3] Lien YH. et. al. Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis. J Clin Invest. 1991;88(1):303. https://www.ncbi.nlm.nih.gov/pubmed/2056123

[4] Strange K. Regulation of solute and water balance and cell volume in the central nervous system. J Am Soc Nephrol. 1992;3(1):12. https://www.ncbi.nlm.nih.gov/pubmed/1391705

[5] Leffler DA, Green PH, Fasano A. Extraintestinal manifestations of coeliac disease. Nat Rev Gastroenterol Hepatol 2015;12:561-571. https://www.ncbi.nlm.nih.gov/pubmed/26260366

[6] Bushara KO. Neurologic presentation of celiac disease. Gastroenterology 2005;128:Suppl 1:S92-97 https://www.ncbi.nlm.nih.gov/pubmed/15825133

[7] Fasano A, Catassi C. Celiac disease. N Engl J Med 2012;367:2419-2426 https://www.ncbi.nlm.nih.gov/pubmed/23252527