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Epigenetics: Why Inheritance Is Weirder Than We Thought

2015-11-18

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Want to learn more about the topic in this week’s video? Here are some keywords/phrases to get your googling started:

epigenetics: genetic control by factors other than an individual’s DNA sequence

epigenetic inheritance: transmittance of information from one generation of an organism to the next that affects the traits of offspring without altering the DNA sequence

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Credits (and Twitter handles):

Script Writer: Kate Yoshida (@KateYoshida)

Script Editor: Emily Elert (@eelert)

Video Illustrator: Omkar Bhagat (@TheCuriousEnggr)

Video Director: Emily Elert (@eelert)

With Contributions From: Alex Reich (@alexhreich), Henry Reich (@minutephysics), Peter Reich and Ever Salazar (@eversalazar)

Music by: Nathaniel Schroeder: http://www.soundcloud.com/drschroeder

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References:

Dias B.G., Ressler, K.J. (2014) Parental olfactory experience influences behavior and neural structure in subsequent generations. Nature Neuroscience 17:89-96. http://www.nature.com/neuro/journal/v17/n1/full/nn.3594.html

Holliday, R. (2006). Epigenetics: a historical overview. Epigenetics 1: 76–80.

http://www.tandfonline.com/doi/pdf/10.4161/epi.1.2.2762

Jones P.A., Takai D. (2001) The role of DNA methylation in mammalian epigenetics. Science 293: 1068–1070. https://www.ufpe.br/biolmol/Artigos_Doutorado_2003_Jan/Science-2001-1068-1070.pdf

Jones S.V., Choi D.C., Davis M., Ressler K.J. (2008) Learning-dependent structural plasticity in the adult olfactory pathway. Journal of Neuroscience 28: 13106–13111. http://www.jneurosci.org/content/28/49/13106.full.pdf

Kaati G., Bygren L.D., Edvinsson S. (2002) Cardiovascular and diabetes mortality determined by nutrition during parents’ and grandparents’ slow growth period. European Journal of Human Genetics 10: 682 – 688. http://www.ncbi.nlm.nih.gov/pubmed/12404098

Morgan H.D., Sutherland H.G., Martin D.I., Whitelaw E. (1999) Epigenetic inheritance at the agouti locus in the mouse. Nature Genetics 23(3): 314-318. http://www.nature.com/ng/journal/v23/n3/full/ng1199_314.html

Pembrey, M. (2002). Time to take epigenetic inheritance seriously. European Journal of Human Genetics 10: 669 – 671. https://moodle.unitec.ac.nz/pluginfile.php/426038/mod_resource/content/0/Epigenetics%20food%20and%20generations.pdf


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