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A Farmer Mistakenly Drank His Own Herbicide. This Is What Happened To His Brain.

2023-08-07

[public] 563K views, 50.2K likes, dislikes audio only

channel thumbChubbyemu
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Patient PT by Wolfgang Nelson, PA Desiree Troy, Review Dr Yue Wu

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Music inspired by R Price, Performed by Chubbyemu

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These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.

References:

Tox and Hound – Fellow Friday – Bipyridyl Herbicide Poisonings: Diquat and Paraquat. https://toxandhound.com/toxhound/ff-di-paraquat/

High-dose diquat poisoning: a case report. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246526/

Urine sodium dithionite test: a useful clinical test for paraquat poisoning. https://journals.lww.com/jcsr/fulltext/2020/09030/urine_sodium_dithionite_test__a_useful_clinical.11.aspx

Human and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment. https://pubmed.ncbi.nlm.nih.gov/29569487/

Case series: Diquat poisoning with acute kidney failure, myocardial damage, and rhabdomyolysis. https://www.frontiersin.org/articles/10.3389/fpubh.2022.991587/full

Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572080/

Human and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment. https://journals.sagepub.com/doi/10.1177/0960327118765330

Ferroptosis: past, present and future. https://www.nature.com/articles/s41419-020-2298-2

Where ferroptosis inhibitors and paraquat detoxification mechanisms intersect, exploring possible treatment strategies. https://pubmed.ncbi.nlm.nih.gov/32061663/

Methylene blue attenuates acute liver injury induced by paraquat in rats. https://www.sciencedirect.com/science/article/abs/pii/S1567576915002088

Case report: Successful outcome of a young patient with rhabdomyolysis and shock caused by diquat poisoning. https://www.frontiersin.org/articles/10.3389/fmed.2023.1116912/full

Bright Red Nuclei. https://n.neurology.org/content/62/4/619

Biochemical Mechanisms of Paraquat Toxicity. Anne P Autor. 1978.

Paraquat Poisoning. UpToDate.

Paraquat and Diquat. Michael Eddleston. Critical Care Toxicology. 2017. https://doi.org/10.1007/978-3-319-17900-1_10

Goldfrank's Toxicology.


Chubbyemu I make medical videos, telling stories in medicine. These are variations on cases I, or my colleagues, have seen in the past. The main goal of these videos are to tell a story about people, as we each have a unique story to tell. This channel was created in September 2015 as a way for me to create something I could call my own. The earlier videos served to teach me how to make a video, as I have no background in filming, editing, etc. That early content was following trends of the time, learning how best to approach my lack of understanding of video. I hold no responsibility over what you do with your or anyone's body after watching any of my videos. You should not recreate any of the presented situations. These videos are not and are not intended to be medical advice. I do not give individualized medical advice over the internet. I am a licensed provider trained and based in the United States.
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